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Comparison of IFN-γ and cytotoxic granule molecule secreting T cell responses between unvaccinated adults and children with and without SARS-CoV-2 infection.

Journal: Scientific Reports

Article Title: Functional T cell response to COVID-19 vaccination with or without natural infection with SARS-CoV-2 in adults and children

doi: 10.1038/s41598-025-95870-6

Figure Lengend Snippet: Comparison of IFN-γ and cytotoxic granule molecule secreting T cell responses between unvaccinated adults and children with and without SARS-CoV-2 infection.

Article Snippet: IFN-γ, perforin, and granzyme B secreting cells were measured in cryopreserved PBMC using human Granzyme B/Perforin Double-Color and IFN-γ ELISPOT kits (Cellular Technology Ltd. (CTL), OH, USA)) following manufacturer’s instructions.

Techniques: Comparison, Infection